She is widowed after Bigby's zephyr son, Ghost, accidentally kills Mr. Web. She does not join her husband in Haven.
After Mr. Dark takes over Fabletown, Miss Muffet is relocated to the Farm along with the other Fables. She supports Geppetto's bid for mayor.
Judging by other characters' weariness and unwillingness to deal with her, as well as her harsh and judgmental language towards Rose Red, she is generally known as an unpleasant and brusque woman.
Miss Muffet is from the nursery rhyme:
- Little Miss Muffet
- Sat on a tuffet,
- Eating her curds and whey;
- Along came a spider,
- Who sat down beside her
- And frightened Miss Muffet away.